Regulatory T cells control type 1-driven immunopathology restraining GM-CSF-producing helper T cells
S. Costa-Pereira, M. Lanzinger, M. Andreadou, N. Nunez, J. Villar-Vesga, F. Prisco, P. Hane, E. Roussel, S. Krishnarajah, R. C. Lindemann, F. Westermann, L. Oberbichler, A. Sethi, A. Fonseca, M. Pinzger, , B. Becher
This study identifies GM-CSF-producing helper T cells as drivers of immunopathology, showing Treg cells restrain them to prevent tissue damage in mice.
bioRxiv · Jan 24, 2024 · PreprintImmunology