The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase
V. Bohl, N. M. Hollmann, T. Melzer, P. Katikaridis, L. Meins, B. Simon, D. Flemming, I. Sinning, J. Hennig, A. Mogk
This study identifies ClpL from Listeria monocytogenes as a potent AAA+ disaggregase that enhances heat resistance by efficiently solubilizing protein aggregates under severe stress.
bioRxiv · Oct 8, 2023 · PreprintBiochemistry