Author

D. Garcia-Cehic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

J. Gregori· 3 shared J. Quer· 3 shared C. Andres· 2 shared F. Rodriguez-Frias· 2 shared J. I. Esteban· 2 shared A. Anton· 1 shared A. I. de Avila· 1 shared A. Jordan-Paiz· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersMicrobiology

J. Gregori

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Amino acid substitutions associated with treatment failure of hepatitis C virus infection

M. E. Soria, C. Garcia-Crespo, B. Martinez-Gonzalez, L. Vazquez-Sirvent, R. Lobo-Vega, A. I. de Avila, I. Gallego, Q. Chen, D. Garcia-Cehic, M. Llorens-Revull, C. Briones, J. Gomez, C. Ferrer-Orta, N. Verdaguer, J. Gregori, , C. Perales

The paper identifies six amino acid substitutions associated with HCV treatment failure that are not resistance-associated substitutions but are highly represented in viral quasispecies.

bioRxiv · Jul 3, 2020Microbiology

Naturally occurring SARS-CoV-2 gene deletions close to the spike S1/S2 cleavage site in the viral quasispecies of COVID19 patients

C. Andres, D. Garcia-Cehic, J. Gregori, M. Pinana, F. Rodriguez-Frias, M. Guerrero, J. Esperalba, A. Rando, L. Goterris, M. G. Codina, S. Quer, M. C. Martin, M. Campins, R. Ferrer, B. Almirante, , J. Quer

The paper analyzes SARS-CoV-2 spike gene deletions in COVID-19 patients, finding frameshift mutations near the S1/S2 cleavage site that may reduce infection severity.

bioRxiv · Jun 3, 2020Microbiology

HIV-1 Protease Evolvability is Affected by Synonymous Nucleotide Recoding

M. Nevot, A. Jordan-Paiz, G. Martrus, C. Andres, D. Garcia-Cehic, J. Gregori, S. Franco, J. Quer, M. A. Martinez

This study compares the development of HIV-1 protease inhibitor resistance between wild-type and synonymously recoded viruses, finding similar resistance phenotypes but distinct mutation repertoires and higher diversity in the recoded virus.

bioRxiv · May 7, 2018Evolutionary Biology