VanRS and CroRS cross-talk revealed by coevolutionary modeling regulates antibiotic resistance in VanA-type vancomycin-resistant Enterococcus faecalis
X.-L. Jiang, U. T. Nguyen, C. Ziegler, D. Goel, K. Palmer, F. Morcos
The paper identifies cross-talk between horizontally acquired and endogenous two-component systems in VanA-type vancomycin-resistant Enterococcus faecalis that contributes to antibiotic synergy.
bioRxiv · May 5, 2022 · PreprintMicrobiology