VanRS and CroRS cross-talk revealed by coevolutionary modeling regulates antibiotic resistance in VanA-type vancomycin-resistant Enterococcus faecalis
X.-L. Jiang, U. T. Nguyen, C. Ziegler…·F. Morcos
The paper identifies cross-talk between horizontally acquired and endogenous two-component systems in VanA-type vancomycin-resistant Enterococcus faecalis that contributes to antibiotic synergy.