Author

D. Greene

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Research Focus:phylogenetics / evolution· 1 Research Focus:variant calling· 1

Frequent Co-Authors

A. G. Lynch· 1 shared A. Gavryushkin· 1 shared A. J. Cutler· 1 shared A. Sanchis-Juan· 1 shared A. Worth· 1 shared C. Fowler· 1 shared C. Penkett· 1 shared C. Samarghitean· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperImmunology

A. G. Lynch

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Acquisition of the L452R mutation in the ACE2-binding interface of Spike protein triggers recent massive expansion of SARS-Cov-2 variants

V. Tchesnokova, H. Kulakesara, L. Larson, V. Bowers, E. Rechkina, D. Kisiela, Y. Sledneva, D. Choudhury, I. Maslova, K. Deng, K. Kutumbaka, H. Geng, C. Fowler, J. D. Ralston, D. Greene, , E. V. Sokurenko

The paper identifies the L452R mutation in the Spike protein as a key driver of recent SARS-CoV-2 variant expansion, particularly in California, and suggests its adaptive significance for viral infectivity and antibody escape.

bioRxiv · Feb 22, 2021Microbiology

Whole-genome sequencing of a sporadic primary immunodeficiency cohort

J. E. D. Thaventhiran, H. Lango Allen, O. S. Burren, W. Rae, D. Greene, E. Staples, Z. Zhang, J. H. R. Farmery, I. Simeoni, J. Maimaris, C. Penkett, J. Stephens, S. V. V. Deevi, A. Sanchis-Juan, N. S. Gleadall, , Kuma

This study uses whole-genome sequencing of a PID cohort to identify genetic mutations and associations, revealing both monogenic and common variant contributions to immune dysfunction.

bioRxiv · May 7, 2020Immunology

Inferring Genetic Interactions From Comparative Fitness Data

K. Crona, A. Gavryushkin, D. Greene, N. Beerenwinkel

This paper develops quantitative tools to infer genetic interactions from fitness rank orders, demonstrating their application across multiple genetic systems.

bioRxiv · Nov 22, 2017Evolutionary Biology