Author

L. Larson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

E. Law· 2 shared P. Argyris· 2 shared R. Harris· 2 shared R. Vogel· 2 shared A. Aguilera· 1 shared A. Alejandro Suarez-Bonnet· 1 shared C. Durfee· 1 shared C. Fowler· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersCancer Biology

E. Law

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Determination of Optimal Nutrient Levels in Baru Seedlings (Dipterix alata Vog.) Using the Mathematical Chance Method

D. Kusano, L. Larson, M. A. Camacho

This paper uses the Mathematical Chance method to determine optimal nutrient ranges for baru seedlings grown in a controlled environment.

bioRxiv · Oct 20, 2023 · PreprintPlant Biology

Acquisition of the L452R mutation in the ACE2-binding interface of Spike protein triggers recent massive expansion of SARS-Cov-2 variants

V. Tchesnokova, H. Kulakesara, L. Larson, V. Bowers, E. Rechkina, D. Kisiela, Y. Sledneva, D. Choudhury, I. Maslova, K. Deng, K. Kutumbaka, H. Geng, C. Fowler, J. D. Ralston, D. Greene, , E. V. Sokurenko

The paper identifies the L452R mutation in the Spike protein as a key driver of recent SARS-CoV-2 variant expansion, particularly in California, and suggests its adaptive significance for viral infectivity and antibody escape.

bioRxiv · Feb 22, 2021Microbiology

An immunogenic model of KRAS-mutant lung cancer for study of targeted therapy and immunotherapy combinations

J. Boumelha, S. de Carne Trecesson, E. Law, P. Romero-Clavijo, M. Coelho, K. Ng, E. Mugarza, C. Moore, S. Rana, D. Caswell, M. Murillo, D. Hancock, P. Argyris, W. Brown, C. Durfee, , J. Downward

This paper develops an immunogenic mouse model of KRAS-mutant lung cancer that responds to immunotherapy and reveals immune responses target endogenous retroviral antigens rather than neoantigens.

bioRxiv · Dec 22, 2020Cancer Biology

APOBEC3A Catalyzes Mutation and Drives Carcinogenesis In Vivo

E. Law, R. Levin-Klein, M. Jarvis, H. Kim, P. Argyris, M. Carpenter, G. Starrett, L. Larson, M. Burns, R. Vogel, S. Stavrou, A. Aguilera, S. Wagner, D. Largaespada, T. Starr, , R. Harris

This study shows APOBEC3A promotes tumorigenesis in mice and supports its role in causing mutations in human cancers.

bioRxiv · Dec 27, 2019Cancer Biology