Laterally transferred macrophage mitochondria acts as a signaling source promoting cancer cell proliferation
C. U. Kidwell, J. R. Casalini, S. Pradeep, S. D. Scherer, D. Greiner, J. S. Johnson, G. S. Olson, J. Rutter, A. L. Welm, T. A. Zangle, M. Roh-Johnson
The paper shows that dysfunctional macrophage mitochondria transferred to cancer cells promote proliferation via ROS-induced ERK signaling.
bioRxiv · Aug 10, 2021Cancer Biology