D. Heussman

Studies of DNA "breathing" by polarization-sweep single-molecule fluorescence microscopy of exciton-coupled (iCy3)2 dimer-labeled DNA fork constructs

This paper introduces a single-molecule fluorescence method to measure DNA breathing dynamics using (iCy3)2 dimer probes, revealing four conformational macrostates in DNA fork constructs.

Using transition density models to interpret experimental optical spectra of exciton-coupled cyanine (iCy3)2 dimer probes of local DNA conformations at or near functional protein binding sites

The paper uses transition density models to analyze optical spectra of (iCy3)2 dimer probes, determining DNA conformational parameters near protein binding sites.

Temperature-dependent local conformations and conformational distributions of cyanine dimer labeled single-stranded -- double-stranded DNA junctions by 2D fluorescence spectroscopy

This study uses 2D fluorescence spectroscopy to analyze temperature-dependent conformational changes in ss-dsDNA junctions labeled with cyanine dimer probes, revealing position-dependent structural disorder.