Studies of DNA "breathing" by polarization-sweep single-molecule fluorescence microscopy of exciton-coupled (iCy3)2 dimer-labeled DNA fork constructs
J. Maurer, C. S. Albrecht, P. Herbert, D. Heussman, A. Chang, P. H. von Hippel, A. H. Marcus
This paper introduces a single-molecule fluorescence method to measure DNA breathing dynamics using (iCy3)2 dimer probes, revealing four conformational macrostates in DNA fork constructs.
bioRxiv · Sep 27, 2023 · PreprintBiophysics