Author

D. Jaime

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J. R. Fallon· 2 shared L. A. Madigan· 2 shared A. MacLean· 1 shared A. Sorn· 1 shared A. Villalta· 1 shared B. Hughes· 1 shared C. Guerrero-Juarez· 1 shared C. Hans· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

J. R. Fallon

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Author profile →

3 papers

Recent·Most cited

MuSK-BMP signaling in adult muscle stem cells maintains quiescence and regulates myofiber size

L. A. Madigan, D. Jaime, I. Chen, J. R. Fallon

This study shows that MuSK-BMP signaling regulates adult muscle stem cell quiescence and myofiber size, with reduced signaling increasing muscle size and function while preserving stemness.

bioRxiv · May 17, 2023 · PreprintCell Biology

Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis

G. COULIS, D. Jaime, C. Guerrero-Juarez, J. Kastenschmidt, P. Farahat, Q. Nguyen, N. Pervolarakis, K. McLinden, L. Thurlow, S. Movahedi, B. Hughes, J. Duarte, A. Sorn, E. Montoya, I. Mozaffar, , A. Villalta

bioRxiv · Apr 18, 2023Immunology

The MuSK-BMP pathway maintains myofiber size in slow muscle through regulation of Akt-mTOR signaling

D. Jaime, L. A. Fish, L. A. Madigan, M. E. Ewing, J. R. Fallon

The paper investigates the MuSK-BMP pathway's role in maintaining slow muscle myofiber size by regulating Akt-mTOR signaling, finding reduced myofiber size and altered RNA metabolism in MuSK-deficient mice.

bioRxiv · Nov 5, 2022Cell Biology