Nebulized delivery of a broadly neutralizing SARS-CoV-2 RBD-specific nanobody prevents clinical, virological and pathological disease in a Syrian hamster model of COVID-19
T. J. Esparza, Y. Chen, N. P. Martin, H. Bielefeldt-Ohmann, R. A. Bowen, W. D. Tolbert, M. J. Pazgier, D. L. Brody
This study shows that nebulized NIH-CoVnb-112 nanobody reduces weight loss, viral burden, and lung pathology in Syrian hamsters infected with SARS-CoV-2.
bioRxiv · Nov 10, 2021Biochemistry