Author

D. L. Mateos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

C. E. Clancy· 1 shared H. Wulff· 1 shared I. Vorobyov· 1 shared J. B. Siegel· 1 shared K. C. Rouen· 1 shared K. Ngo· 1 shared M. A. Riley· 1 shared M. M. Chinn· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

C. E. Clancy

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Computationally Driven Design of Novel BACE-1 Inhibitors for Alzheimer's Disease

M. M. Chinn, D. L. Mateos, M. A. Riley, J. B. Siegel

This study designs new BACE-1 inhibitors using computational modeling, showing improved docking scores compared to Verubecestat for Alzheimer's disease treatment.

bioRxiv · Nov 15, 2023 · PreprintBiochemistry

Elucidating Molecular Mechanisms of Protoxin-2 State-specific Binding to the Human NaV1.7 Channel

K. Ngo, D. L. Mateos, Y. Han, K. C. Rouen, S.-H. Ahn, H. Wulff, C. E. Clancy, V. Yarov-Yarovoy, I. Vorobyov

This study uses computational modeling to investigate how protoxin-2 binds to different states of the hNaV1.7 channel, identifying key residues and lipid interactions that contribute to its selectivity.

bioRxiv · Feb 27, 2023Biophysics