Author

D. Lal

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Biophysics· 1

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Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Brunklaus· 1 shared C. Eng· 1 shared E. P. Palma· 1 shared F. Cheng· 1 shared I. Helbig· 1 shared I. N. Smith· 1 shared L. Montanucci· 1 shared N. Bhattarai· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

A. Brunklaus

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1 paper

Recent·Most cited

Molecular dynamics simulations reveal molecular mechanisms for the gain and loss of function effects of four SCN2A variants

N. Bhattarai, L. Montanucci, T. Brunger, E. P. Palma, W. Martin, I. N. Smith, C. Eng, F. Cheng, I. Helbig, R. Moller, A. Brunklaus, S. Schorge, D. Lal

The paper uses molecular dynamics simulations to analyze four SCN2A variants, revealing how they affect channel structure and function, with R937C being the most unstable.

bioRxiv · Feb 19, 2024 · PreprintBiophysics