Author

R. Moller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

K. Oishi· 2 shared S. Horiuchi· 2 shared A. Brunklaus· 1 shared A. C. Borczuk· 1 shared A. Hald· 1 shared A. Jiang· 1 shared A. Kodra· 1 shared A. Morris· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

K. Oishi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Molecular dynamics simulations reveal molecular mechanisms for the gain and loss of function effects of four SCN2A variants

N. Bhattarai, L. Montanucci, T. Brunger, E. P. Palma, W. Martin, I. N. Smith, C. Eng, F. Cheng, I. Helbig, R. Moller, A. Brunklaus, S. Schorge, D. Lal

The paper uses molecular dynamics simulations to analyze four SCN2A variants, revealing how they affect channel structure and function, with R937C being the most unstable.

bioRxiv · Feb 19, 2024 · PreprintBiophysics

Cystic fibrosis systemic immune profile is associated with lung microbes and characterized by widespread alterations in the innate and adaptive immune compartments

E. Rossi, M. Lausen Nielsen, N. Friesgaard Obro, C. A. Colque, B. U. Nielsen, R. Moller, C. De Gier, A. Hald, M. Skov, T. Pressler, S. Molin, S. R. Ostrowski, H. V. Marquart, H. K. Johansen

This study identifies a specific immune profile in cystic fibrosis patients linked to lung microbiota and immune dysregulation, offering potential targets for treatment.

bioRxiv · Aug 23, 2023Immunology

The Lion's Share: Implications of carnivore diet on endangered herbivores in Tsavo

E. King, S. Chakrabarti, F. Lala, S. Nyaga, G. Waiguchu, P. I. Chiyo, J. Kimaile, R. Moller, P. Omondi, A. Morris, J. Bump

The paper analyzes lion diet in Tsavo, Kenya, finding that lions disproportionately consume endangered hirola and Grevys zebra despite their low population sizes.

bioRxiv · Jul 8, 2023 · PreprintEcology

SARS-CoV-2 infection results in lasting and systemic perturbations post recovery

J. J. Frere, R. A. Serafini, K. D. Pryce, M. Zazhytska, K. Oishi, I. Golynker, M. Panis, J. Zimering, S. Horiuchi, D. A. Hoagland, R. Moller, A. Ruiz, J. B. Overdevest, A. Kodra, P. D. Canoll, , B. tenOever

This study compares short- and long-term systemic responses to SARS-CoV-2 and IAV in golden hamsters, finding persistent inflammation in olfactory tissues post-recovery.

bioRxiv · Jan 18, 2022Microbiology

Human organ chip-enabled pipeline to rapidly repurpose therapeutics during viral pandemics

L. Si, H. Bai, M. Rodas, W. Cao, C. Y. Oh, A. Jiang, R. Moller, D. Hoagland, K. Oishi, S. Horiuchi, S. Uhl, D. Blanco-Melo, R. A. Albrecht, W.-C. Liu, T. Jordan, , D. E. Ingber

This paper demonstrates the use of human organ chips to rapidly repurpose therapeutics for viral pandemics, identifying amodiaquine as a potential treatment for SARS-CoV-2.

bioRxiv · Apr 13, 2020 · PreprintMicrobiology