Qualifying a human Liver-Chip for predictive toxicology: Performance assessment and economic implications
L. Ewart, A. Apostolou, S. A. Briggs, C. V. Carman, J. T. Chaff, A. R. Heng, S. Jadalannagari, J. Janardhanan, K.-J. Jang, S. R. Joshipura, M. Kadam, M. Kanellias, V. J. Kujala, G. Kulkarni, C. Y. Le, , D. Levner
The paper evaluates a Liver-Chip's ability to predict drug-induced liver injury and estimates its economic impact in pharmaceutical R&D.
bioRxiv · Dec 14, 2021 · PreprintPharmacology & Toxicology