Author

D. M. Brooks

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:differential expression· 1

Frequent Co-Authors

P. R. Secor· 4 shared D. R. Faith· 3 shared C. M. Schwartzkopf· 2 shared M. Kinnersley· 2 shared A. A. Dandekar· 1 shared A. J. Robinson· 1 shared A. K. Schmidt· 1 shared A. L. Sapiro· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersMicrobiology

P. R. Secor

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Author profile →

4 papers

Recent·Most cited

Characterization and genomic analysis of the Lyme disease spirochete bacteriophage phiBB-1

D. R. Faith, M. Kinnersley, D. M. Brooks, D. Drecktrah, L. S. Hall, E. Luo, A. Santiago-Frangos, J. Wachter, S. Samuels, P. R. Secor

This study characterizes the bacteriophage phiBB-1 using proteomics and long-read sequencing, revealing its packaging mechanisms and role in gene transfer in Borrelia burgdorferi.

PLOS Pathogens · Apr 1, 2024Peer-reviewedMicrobiology

Inhibition of PQS signaling by the Pf bacteriophage protein PfsE enhances viral replication in Pseudomonas aeruginosa

C. M. Schwartzkopf, V. L. Taylor, M.-C. Groleau, D. R. Faith, A. K. Schmidt, T. L. Lamma, D. M. Brooks, E. Deziel, K. L. Maxwell, P. R. Secor

The paper identifies PfsE as a Pf phage protein that inhibits PQS quorum sensing and type IV pili extension, enhancing viral replication and protecting the host from competing phages.

bioRxiv · Aug 25, 2023Microbiology

Longitudinal map of transcriptome changes in the Lyme pathogen Borrelia burgdorferi during tick-borne transmission

A. L. Sapiro, B. M. Hayes, R. F. Volk, J. Y. Zhang, D. M. Brooks, C. Martyn, A. Radkov, Z. Zhao, M. Kinnersley, P. R. Secor, B. W. Zaro, S. Chou

This study maps transcriptome changes in Borrelia burgdorferi during tick-borne transmission by analyzing gene expression over four days in ticks.

bioRxiv · Nov 9, 2022 · PreprintMicrobiology

Tripartite interactions between filamentous Pf4 bacteriophage, Pseudomonas aeruginosa, and bacterivorous nematodes

C. M. Schwartzkopf, A. J. Robinson, M. Ellenbecker, D. R. Faith, D. M. Brooks, L. Lewerke, E. Voronina, A. A. Dandekar, P. R. Secor

This study shows that curing Pseudomonas aeruginosa of Pf4 phage infection increases virulence in C. elegans by enhancing PQS quorum sensing and pyocyanin production, but nematodes unable to detect bacterial pigments are more susceptible to the Pf4-cured strain.

bioRxiv · Oct 11, 2022Microbiology