Pre-mRNA Splicing Factor U2AF2 Recognizes Distinct Conformations of Nucleotide Variants at the Center of the pre-mRNA Splice Site Signal
E. Glasser, D. Maji, G. Biancon, A. M. Keedakkatt Puthenpeedikakkal, C. Cavender, T. Tebaldi, M. J. Pulvino, J. L. Jenkins, D. H. Mathews, S. Halene, C. L. Kielkopf
This study investigates how U2AF2 recognizes different nucleotides at the center of the Py tract in pre-mRNA splice sites using structural and functional analyses.
bioRxiv · Sep 27, 2021Biophysics