T. Tebaldi

Impact of Memory T Cells on SARS-COV-2 Vaccine Response in Hematopoietic Stem Cell Transplant

This study evaluates SARS-CoV-2 vaccine responses in HSCT recipients, finding memory T cell defects linked to reduced T cell responses despite humoral responses.

NOC1 is a Direct MYC Target, and Its Protein Interactome Dissects Its Activity in Controlling Nucleolar Function

This study identifies NOC1 as a direct MYC target and shows its role in nucleolar function through protein interactions and structural changes.

Pre-mRNA Splicing Factor U2AF2 Recognizes Distinct Conformations of Nucleotide Variants at the Center of the pre-mRNA Splice Site Signal

This study investigates how U2AF2 recognizes different nucleotides at the center of the Py tract in pre-mRNA splice sites using structural and functional analyses.

Multi-omics profiling of U2AF1 mutants dissects pathogenic mechanisms affecting RNA granules in myeloid malignancies

This study uses multi-omics profiling to analyze U2AF1 mutations in myeloid malignancies, revealing altered RNA binding, splicing, and stress granule formation.

Influence of the microenvironment on the modulation of the host response by the typhoid toxin

This study investigates how typhoid toxin modulates host immune responses in health and disease by inducing DNA damage and senescence, with effects dependent on the host's inflammatory state.

A Highly Efficient and Faithful MDS Patient-Derived Xenotransplantation Model for Pre-Clinical Studies

This paper develops a novel MDS patient-derived xenotransplantation model in MISTRG mice that faithfully represents all MDS subtypes and enables effective drug testing.

HuD is a neural enhancer of global translation acting on mTORC1-responsive genes and sponged by the Y3 small non-coding RNA