Author

D. Mancinotti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:genetic perturbation / CRISPR· 2 Organism:plant (other)· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:fungi (other)· 1 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

F. Geu-Flores· 3 shared T. Yang· 2 shared A. H. Schulman· 1 shared A. Vandenberg· 1 shared C. Crocoll· 1 shared D. Angra· 1 shared D. Heavens· 1 shared D. M. O'Sullivan· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBiochemistry

F. Geu-Flores

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Author profile →

3 papers

Recent·Most cited

Metabolic engineering of narrow-leafed lupin for the production of enantiomerically pure (-)-sparteine

D. Mancinotti, T. Yang, F. Geu-Flores

This study engineered narrow-leafed lupin to produce enantiomerically pure (-)-sparteine by knocking out a key enzyme, achieving 99% enantiomeric excess.

bioRxiv · Apr 26, 2024Biochemistry

An improved Nicotiana benthamiana bioproduction chassis provides novel insights into nicotine biosynthesis

K. Vollheyde, Q. M. Dudley, T. Yang, M. T. Oz, D. Mancinotti, M. O. Fedi, D. Heavens, G. Linsmith, M. Chhetry, M. A. Smedley, W. A. Harwood, D. Swarbreck, F. Geu-Flores, N. Patron

This study improves Nicotiana benthamiana for bioproduction by reducing nicotine levels and provides insights into the role of BBLs in nicotine biosynthesis.

bioRxiv · Mar 6, 2023 · PreprintPlant Biology

VC1 catalyzes a key step in the biosynthesis of vicine from GTP in faba bean

E. Bjornsdotter, M. Nadzieja, W. Chang, L. Escobar-Herrera, D. Mancinotti, D. Angra, H. Khazaei, C. Crocoll, A. Vandenberg, F. L. Stoddard, D. M. O'Sullivan, J. Stougaard, A. H. Schulman, S. U. Andersen, F. Geu-Flores

The paper identifies VC1 as the enzyme catalyzing vicine biosynthesis from GTP in faba bean and shows its role in vicine content regulation.

bioRxiv · Feb 26, 2020 · PreprintBiochemistry