Checkpoint signaling and error correction require regulation of the MPS1 T-loop by PP2A-B56
U. Gruneberg, D. Hayward, J. Bancroft, D. Mangat, T. Alfonso-Perez, S. Dugdale, J. McCarthy, F. A. Barr
The paper shows that PP2A-B56 regulates MPS1 T-loop autophosphorylation, controlling MPS1 activity and mitotic progression.
bioRxiv · May 3, 2019Cell Biology