Author

F. A. Barr

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 5 Approach:experimental assay· 5 Organism:human· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 1 Assay:proteomics· 1

Frequent Co-Authors

T. Sobajima· 3 shared U. Gruneberg· 3 shared D. Hayward· 2 shared A. Gerondopoulos· 1 shared C. Batley· 1 shared C. Neary· 1 shared D. Mangat· 1 shared E. Poser· 1 shared

Activity by Year

2019-2023 · peak 2/yr

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10 top collaborators · 20 mutual co-author links

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3 shared papersCell Biology

T. Sobajima

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5 papers

Recent·Most cited

MDM2 acts as a timer reporting the length of mitosis

L. Fulcher, T. Sobajima, I. Gibbs-Seymour, F. A. Barr

The paper identifies MDM2 as a timer that detects mitosis duration, triggering G1 arrest when mitosis is prolonged.

bioRxiv · May 26, 2023Cell Biology

PP6 regulation of Aurora A-TPX2 limits NDC80 phosphorylation and mitotic spindle size

T. Sobajima, K. Kowalczyk, S. Skylakakis, D. Hayward, L. J. Fulcher, C. Neary, C. Batley, S. Kurlekar, E. Roberts, U. Gruneberg, F. A. Barr

The paper shows that PP6 regulates Aurora A-TPX2 to control NDC80 phosphorylation and mitotic spindle size, preventing defective nuclear structure.

bioRxiv · May 23, 2022Cell Biology

A baton-relay mechanism for ER retrieval signal capture and proofreading by the KDEL receptor

A. Gerondopoulos, P. Bräuer, T. Sobajima, Z. Wu, J. L. Parker, P. Biggin, F. A. Barr, S. Newstead

The paper investigates the KDEL receptor's mechanism for capturing and proofreading ER retrieval signals, revealing a baton-relay mechanism and selective proofreading steps.

bioRxiv · Mar 21, 2021Cell Biology

Aurora A promotes chromosome congression by activating the condensin-dependent pool of KIF4A

E. Poser, R. Caous, U. Gruneberg, F. A. Barr

The paper shows Aurora A phosphorylates the condensin I-dependent pool of KIF4A, promoting chromosome congression during mitosis.

bioRxiv · May 27, 2019Cell Biology

Checkpoint signaling and error correction require regulation of the MPS1 T-loop by PP2A-B56

U. Gruneberg, D. Hayward, J. Bancroft, D. Mangat, T. Alfonso-Perez, S. Dugdale, J. McCarthy, F. A. Barr

The paper shows that PP2A-B56 regulates MPS1 T-loop autophosphorylation, controlling MPS1 activity and mitotic progression.

bioRxiv · May 3, 2019Cell Biology