Author

D. Matzek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

B. Popper· 2 shared A. Imhof· 1 shared A. Krug· 1 shared A. Kuenkele· 1 shared B. L. Cadilha· 1 shared B. Stecher· 1 shared D. Anz· 1 shared D. Ring· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

B. Popper

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma

T. L. B. Hoelting, F. Cidre-Aranaz, D. Matzek, B. Popper, S. J. Jacobi, J. Li, I. Piseddu, B. L. Cadilha, S. Ledderose, J. Zwilling, S. Ohmura, D. Anz, A. Kuenkele, F. Klauschen, T. G. P. Gruenewald, M. M. L. Knott

This paper develops a gene expression strategy that exploits neomorphic DNA-binding of fusion transcription factors in pediatric sarcomas to deliver therapeutic payloads with tumor-specific efficacy.

bioRxiv · Jan 5, 2022Cancer Biology

Helicobacter hepaticus as disease driver in a novel CD40-mediated model of colitis

V. Friedrich, I. Forne, D. Matzek, D. Ring, B. Popper, L. Jochum, S. Spriewald, T. Straub, A. Imhof, A. Krug, B. Stecher, T. Brocker

This study identifies Helicobacter hepaticus as a disease driver in a CD40-mediated colitis model by showing its role in inducing inflammatory immune responses through specific antigen recognition.

bioRxiv · Apr 21, 2020 · PreprintImmunology