Author

D. Anz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Assay:CRISPR screen· 1 Approach:deep learning· 1

Frequent Co-Authors

I. Piseddu· 2 shared A. Holtermann· 1 shared A. Kuenkele· 1 shared B. L. Cadilha· 1 shared B. Popper· 1 shared C. Schultheiss· 1 shared D. Matzek· 1 shared F. Cidre-Aranaz· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

I. Piseddu

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Mutation-specific CAR T cells as precision therapy for IGLV3-21R110 expressing high-risk chronic lymphocytic leukemia

F. Maerkl, C. Schultheiss, M. Ali, S.-S. Chen, L. Egli, J. Mietz, O. Chijoke, L. Paschold, S. Spajic, A. Holtermann, J. Doerr, S. Stock, I. Piseddu, D. Anz, M. Duehren-von Minden, , M. Binder

This study develops CAR T cells targeting a specific mutation in CLL to selectively kill cancer cells while sparing healthy B cells.

bioRxiv · Sep 29, 2023 · PreprintCancer Biology

Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma

T. L. B. Hoelting, F. Cidre-Aranaz, D. Matzek, B. Popper, S. J. Jacobi, J. Li, I. Piseddu, B. L. Cadilha, S. Ledderose, J. Zwilling, S. Ohmura, D. Anz, A. Kuenkele, F. Klauschen, T. G. P. Gruenewald, M. M. L. Knott

This paper develops a gene expression strategy that exploits neomorphic DNA-binding of fusion transcription factors in pediatric sarcomas to deliver therapeutic payloads with tumor-specific efficacy.

bioRxiv · Jan 5, 2022Cancer Biology