Author

D. McCloskey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:statistical model· 1 Approach:variational autoencoder· 1

Frequent Co-Authors

A. M. Feist· 1 shared B. O. Palsson· 1 shared C. Cheng· 1 shared C. Igel· 1 shared C. Olson· 1 shared E. J. O'Brien· 1 shared J. Utrilla· 1 shared M. Nielsen· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

A. M. Feist

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2 papers

Recent·Most cited

Bi-modal Variational Autoencoders for Metabolite Identification Using Tandem Mass Spectrometry

S. Kutuzova, C. Igel, M. Nielsen, D. McCloskey

The paper introduces a bi-modal variational autoencoder to identify metabolites from tandem mass spectrometry data by learning from unpaired molecule structures and spectra.

bioRxiv · Aug 3, 2021 · PreprintBiochemistry

Laboratory evolution reveals a two-dimensional rate-yield tradeoff in microbial metabolism

C. Cheng, E. J. O'Brien, D. McCloskey, J. Utrilla, C. Olson, R. A. LaCroix, T. E. Sandberg, A. M. Feist, B. O. Palsson, Z. A. King

This study identifies a two-dimensional rate-yield tradeoff in evolved E. coli strains using multi-scale modeling.

bioRxiv · Sep 17, 2018Microbiology