Author

C. Olson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 5 Research Focus:drug response / drug discovery· 4 Approach:experimental assay· 4 Organism:human· 4 Assay:metabolomics· 3 Approach:statistical model· 3 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2

Frequent Co-Authors

H. Tsunemoto· 4 shared J. Pogliano· 4 shared R. Szubin· 4 shared S. Poudel· 4 shared V. Nizet· 4 shared Y. Seif· 4 shared A. Feist· 3 shared A. Lamsa· 3 shared

Activity by Year

2018-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMicrobiology

H. Tsunemoto

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Ketogenic diet therapy for pediatric epilepsy is associated with alterations in the human gut microbiome that confer seizure resistance in mice

G. R. Lum, S. M. Ha, C. Olson, M. Blencowe, J. Paramo, B. Reyes, J. Matsumoto, X. Yang, E. Y. Hsiao

This study shows that the ketogenic diet alters the gut microbiome in children with epilepsy, and transferring these microbes to mice increases seizure resistance.

bioRxiv · Mar 17, 2023Microbiology

Capturing and Recreating Diverse Antibody Repertoires as Multivalent Recombinant Polyclonal Antibody Drugs

S. M. Keating, R. A. Mizrahi, M. S. Adams, M. A. Asensio, E. Benzie, K. P. Carter, Y. Chiang, R. C. Edgar, B. K. Gautam, A. Gras, J. Leong, R. Leong, Y. W. Lim, V. A. Manickam, A. V. Medina-Cucurella, , E Meyer

This paper demonstrates a technology to capture and recreate diverse antibody repertoires as multivalent recombinant drugs, showing applications against SARS-CoV-2, Zika virus, and graft-versus-host disease.

bioRxiv · Aug 5, 2020 · PreprintImmunology

Revealing 29 sets of independently modulated genes in Staphylococcus aureus, their regulators and role in key physiological responses

S. Poudel, H. Tsunemoto, Y. Seif, A. V. Sastry, R. Szubin, S. Xu, H. Machado, C. Olson, A. Anand, J. Pogliano, V. Nizet, B. Palsson

This paper identifies 29 independently modulated gene sets in S. aureus using ICA, linking them to regulators and physiological responses.

Proceedings of the National Academy of Sciences · Jul 2, 2020Peer-reviewedMicrobiology

Characterizing the response of Acinetobacter baumannii ATCC 17978 to azithromycin in multiple in vitro growth conditions

N. A. Dillon, Y. Seif, H. Tsunemoto, S. Poudel, M. Meehan, R. Szubin, C. Olson, A. Rajput, G. Alarcon, A. Lamsa, A. Vrbanac, J. Sugie, S. Dahesh, J. Monk, P. Dorrestein, , V. Nizet

This study examines how MDR A. baumannii responds to azithromycin in different growth conditions using multiple analytical techniques.

bioRxiv · May 19, 2020 · PreprintMicrobiology

Identifying the effect of vancomycin on HA-MRSA strains using bacteriological and physiological media

A. Rajput, S. Poudel, H. Tsunemoto, M. Meehan, R. Szubin, C. Olson, Y. Seif, A. Lamsa, N. Dillon, A. Vrbanac, J. Sugie, S. Dahesh, J. Monk, P. Dorrestein, J. Pogliano, , B. O. Palsson

The paper examines vancomycin's effect on HA-MRSA USA100 strains using bacteriological and physiological media through growth curves, RNA sequencing, and exo-metabolomics.

bioRxiv · May 6, 2020 · PreprintMicrobiology

Profiling the effect of nafcillin on HA-MRSA D592 using bacteriological and physiological media

Y. Seif, S. Poudel, H. Tsunemoto, R. Szubin, M. J. Meehan, C. Olson, A. Rajput, G. Alarcon, A. Lamsa, N. Dillon, A. Vrbanac, J. Sugie, S. Daesh, J. Monk, P. Dorrestein, , V. Nizet

This study investigates how nafcillin affects HA-MRSA D592 in different media types, revealing media-dependent antibiotic activity through multi-dimensional analysis.

bioRxiv · Apr 30, 2020 · PreprintMicrobiology

Laboratory evolution reveals a two-dimensional rate-yield tradeoff in microbial metabolism

C. Cheng, E. J. O'Brien, D. McCloskey, J. Utrilla, C. Olson, R. A. LaCroix, T. E. Sandberg, A. M. Feist, B. O. Palsson, Z. A. King

This study identifies a two-dimensional rate-yield tradeoff in evolved E. coli strains using multi-scale modeling.

bioRxiv · Sep 17, 2018Microbiology