Abl kinase deficiency promotes AKT pathway activation and prostate cancer progression and metastasis
M. A. Marchal, D. Moose, A. Varzavand, D. Taylor, J. A. Brown, M. D. Henry, C. S. Stipp
bioRxiv · May 19, 2020 · PreprintCancer Biology
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M. A. Marchal, D. Moose, A. Varzavand, D. Taylor, J. A. Brown, M. D. Henry, C. S. Stipp
bioRxiv · May 19, 2020 · PreprintCancer Biology
C. Yong, D. Moose, N. Bannick, M. Vanneste, R. Svensson, P. Breheny, J. Brown, M. Cohen, M. Henry
The paper improves a prostate cancer mouse model with a bioluminescent reporter to monitor tumor progression and shows that double knockout of Pten and Trp53 leads to castrate-resistant, locally invasive tumors.
bioRxiv · Apr 23, 2020Cancer Biology