Tumors Exploit Dedicated Intracellular Vesicles to Program T cell Responses
E. W. Roberts, M. K. Ruhland, E. Cai, A. M. Mujal, K. Marchuk, C. Beppler, D. Nam, N. K. Serwas, M. Binnewies, M. F. Krummel
The paper shows myeloid cells transfer tumor antigen-laden vesicles to APCs, directing T cell responses away from memory phenotypes.
bioRxiv · Jul 4, 2019 · PreprintImmunology