Origins and timing of emerging lesions in advanced renal cell carcinoma
A. Wallace, S. Porten, A. A. Lo, D. Oreper, N. Lounsbury, C. Havnar, X. Pechuan-Jorge, O. Zill, M. Meng
This study uses multi-region sequencing to analyze the origins and timing of tumor lesions in advanced renal cell carcinoma, finding that metastases often emerge early and VTT forms later through inflammatory processes.
bioRxiv · Jun 27, 2021Cancer Biology