R. Jones

AN UPDATED POPULATION ESTIMATE FOR NORTHERN GANNETS ACROSS THEIR NORTH-EAST ATLANTIC BREEDING RANGE FOLLOWING THE 2022 OUTBREAK OF HIGH PATHOGENICITY AVIAN INFLUENZA

This study updates the population estimate for northern gannets in the North-East Atlantic after a 2022 HPAI outbreak, showing a 17% decline in occupied sites.

Evaluating Paraspinal Muscle Response and Compensation via Musculoskeletal Modeling in Spinal Stenosis Surgeries

This study compares muscle force changes in different spinal stenosis surgeries using musculoskeletal modeling, finding that laminotomy reduces muscle compensation compared to laminectomy.

A Lung Cancer Mouse Model Database

The paper establishes a database of lung cancer mouse models to improve data comparison and translational relevance by aligning mouse mutations with human lung cancer mutations.

Delayed Center of Mass Feedback in Elderly Humans Leads to Greater Muscle Co-Contraction and Altered Balance Strategy under Perturbed Balance: a Predictive Musculoskeletal Simulation Study

This study uses predictive musculoskeletal simulations to show that delayed center of mass feedback in elderly humans increases muscle co-contraction and alters balance strategies during perturbations.

Proteomic Features of Adolescents and Young Adults with Soft Tissue Tumours

This study compares proteomic profiles of adolescents and young adults with soft tissue tumours to older adults, identifying age-specific molecular features and potential therapeutic targets.

Proteomic characterisation of Sarculator nomogram-defined risk groups in soft tissue sarcomas of the extremities and trunk wall

This study identifies a DNA replication protein signature (SPM6) that improves risk stratification in soft tissue sarcomas when combined with the Sarculator nomogram.

Microfluidic antibody profiling after repeated SARS-CoV-2 vaccination links antibody affinity and concentration to impaired immunity and variant escape in patients on anti-CD-20 therapy

Glyceroglycolipids are essential for Burkholderia cenocepacia intracellular survival by preventing phagolysosome acidification

Neglected no longer: Phylogenomic resolution of higher-level relationships in Solifugae

This study generates a phylogenomic dataset for Solifugae using ultraconserved elements, revealing a well-resolved phylogeny and divergence times, supporting a diversification history driven by continental breakup.

Characterising replisome disassembly in human cells

This study characterizes replisome disassembly in human cells, showing that Cullin2, LRR1, and p97 are required, and that replication stress occurs with inhibitor treatment.

PGC-1β maintains mitochondrial metabolism and restrains inflammatory gene expression

This study shows that PGC-1β promotes mitochondrial metabolism and suppresses inflammatory gene expression in dendritic cells.

Proteomic profiling identifies co-regulated expression of splicing factors as a characteristic feature of intravenous leiomyomatosis

This study identifies co-regulated splicing factor expression as a defining feature of intravenous leiomyomatosis through proteomic analysis.

Reproducibility problem with a proposed standard method to measure disinfection efficacy

This study assesses the reproducibility of a proposed disinfectant efficacy method across four labs, finding poor inter-lab reproducibility despite standardization.

Refractive-index matching enhanced polarization-sensitive optical coherence tomography quantification in human brain tissue

This study improves PS-OCT quantification in human brain tissue using refractive index matching, reducing noise and improving birefringence measurements in both white and gray matter.

Phosphorus stress induces the synthesis of novel glycolipids in Pseudomonas aeruginosa that confer protection against a last-resort antibiotic

This paper shows that Pseudomonas aeruginosa produces novel glycolipids under phosphorus stress, which protect it from polymyxin B antibiotic.

Systemic and mucosal mobilization of granulocyte subsets during lentivirus infection

This study examines granulocyte subset dynamics in systemic and mucosal tissues during lentivirus infection in rhesus macaques, finding altered frequencies in chronic infection, particularly in gastrointestinal mucosae.

Indication-specific tumor evolution and its impact on neoantigen targeting and biomarkers for individualized cancer immunotherapies

The paper analyzes tumor evolution across cancer types to identify factors affecting neoantigen targeting in immunotherapy.

Human antigen-specific memory natural killer cell responses develop against HIV-1 and influenza virus and are dependent on MHC-E restriction

This study shows human NK cells develop antigen-specific memory against HIV-1 and influenza via MHC-E restriction, validated through single-cell cloning and biomarker analysis.

Arbovirus Vectors of Epidemiological Concern in the Americas: A Scoping Review of Entomological Studies on Zika, Dengue and Chikungunya Virus Vectors

This review summarizes entomological studies on Zika, dengue, and chikungunya virus vectors in the Americas, identifying key factors affecting transmission and highlighting knowledge gaps.

c-Jun Overexpressing CAR-T Cells are Exhaustion-Resistant and Mediate Enhanced Antitumor Activity

This study shows that overexpressing c-Jun in CAR-T cells reduces exhaustion and improves antitumor activity in vivo.

The transcription factors TFEB and TFE3 link the FLCN-AMPK signaling axis to innate immune response and pathogen resistance

This study identifies a conserved mechanism linking FLCN-AMPK signaling to TFEB/TFE3 activation, enhancing innate immunity and pathogen resistance across species.