Author

R. Bourgon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1

Frequent Co-Authors

A.-J. Tong· 2 shared C. Blanchette· 2 shared S. Jhunjhunwala· 2 shared A. A. Cass· 1 shared A. A. Lo· 1 shared A. Heidersbach· 1 shared A. Wallace· 1 shared A.-H. Capietto· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

A.-J. Tong

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Author profile →

3 papers

Recent·Most cited

HLApollo: A superior transformer model for pan-allelic peptide-MHC-I presentation prediction, with diverse negative coverage, deconvolution and protein language features.

W. J. Thrift, N. W. Lounsbury, Q. Broadwell, A. Heidersbach, E. Freund, Q. Phung, Y. Abdolazimi, J. Chen, A.-H. Capietto, A.-J. Tong, C. M. Rose, C. Blanchette, J. Lill, B. Haley, L. Delamarre, , S. Jhunjhunwala

HLApollo improves MHC-I peptide presentation prediction with a transformer model, showing better performance than existing methods and offering pan-allelic generalization.

bioRxiv · Dec 8, 2022 · PreprintImmunology

Indication-specific tumor evolution and its impact on neoantigen targeting and biomarkers for individualized cancer immunotherapies

A. A. Lo, A. Wallace, D. Oreper, N. Lounsbury, C. Havnar, X. Pechuan-Jorge, T. D. Wu, R. Bourgon, R. Jones, K. Krogh, G.-Y. Yang, O. A. Zill

The paper analyzes tumor evolution across cancer types to identify factors affecting neoantigen targeting in immunotherapy.

bioRxiv · Mar 15, 2021Cancer Biology

Transposable Element Expression In Tumors Is Associated With Immune Infiltration And Increased Antigenicity

Y. Kong, C. Rose, A. A. Cass, M. Darwish, S. Lianoglou, P. M. Haverty, A.-J. Tong, C. Blanchette, I. Mellman, R. Bourgon, G. John, S. Jhunjhunwala, M. L. Albert, H. Chen-Harris

The paper shows that transposable element expression in tumors correlates with immune infiltration and increased antigenicity, suggesting potential synergy with immunotherapy.

bioRxiv · Aug 9, 2018Cancer Biology