D. P. Bendixsen

Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer

The paper identifies two divergent structural variation trajectories in HGSOC that impact patient survival and reveals novel candidate driver genes and mtDNA mutations associated with prognosis.

Hybrid adaptation is hampered by Haldane's sieve

The paper shows that hybrid yeast adaptation is slowed by Haldane's sieve due to slower loss of heterozygosity and incomplete dominance of adaptive mutations.

The dynamics of adaptation to stress from standing genetic variation and de novo mutations

This study tracks fitness and genomic changes in yeast populations under stress using experimental evolution, showing rapid adaptation and parallel genetic changes.

Genotype network intersections promote evolutionary innovation

This study investigates how intersections of genotype networks in catalytic RNA molecules enable evolutionary innovation by allowing sequences to perform multiple functions.