Modulation of GPR133 (ADGRD1) Signaling by its Intracellular Interaction Partner Extended Synaptotagmin 1 (ESYT1)
G. Stephan, W. Liu, J. Frenster, N. Ravn-Boess, D. Bready, J. Cai, D. Fenyo, T. A. Neubert, D. Placantonakis
This study identifies ESYT1 as an intracellular modulator of GPR133 signaling, showing that Ca2+ levels influence their interaction and affect cAMP levels in glioblastoma cells.
bioRxiv · Feb 9, 2023Cell Biology