Mechanism and effects of the skeletal muscle Nav1.4 inhibition by cannabidiol
M.-R. Ghovanloo, K. Choudhury, T. S. Bandaru, M. A. Fouda, K. Rayani, R. Rusinova, T. Phaterpekar, K. Nelkenbrecher, A. R. Watkins, D. Poburko, J. Thewalt, O. S. Andersen, L. Delemotte, S. J. Goodchild, P. Ruben
This study investigates how cannabidiol inhibits Nav1.4 channels in skeletal muscle by modulating membrane elasticity and directly interacting with the channel pore.
bioRxiv · Jun 30, 2020Biophysics