Non-toxigenic Vibrio cholerae challenge strains for evaluating vaccine efficacy and inferring mechanisms of protection
B. Fakoya, K. Hullahalli, D. H. F. Rubin, D. R. Leitner, R. Chilengi, D. Sack, M. K. Waldor
This study develops non-toxigenic V. cholerae challenge strains to evaluate vaccine efficacy and infer protection mechanisms, showing they accurately measure colonization reduction and vibriocidal antibody responses.
bioRxiv · Dec 17, 2021 · PreprintMicrobiology