MicrobiologybioRxivPreprint
Non-toxigenic Vibrio cholerae challenge strains for evaluating vaccine efficacy and inferring mechanisms of protection
B. Fakoya, K. Hullahalli, D. H. F. Rubin…·M. K. Waldor
This study develops non-toxigenic V. cholerae challenge strains to evaluate vaccine efficacy and infer protection mechanisms, showing they accurately measure colonization reduction and vibriocidal antibody responses.