Structure of a Rhs effector clade domain identifies new mechanistic insights into type VI secretion system toxin delivery.
B. K. Hayes, M. Harper, H. Venugopal, J. M. Lewis, A. Wright, J. R. Steele, D. Steer, R. B. Schittenhelm, J. D. Boyce, S. McGowan
The paper presents the structure of Tse15, a T6SS Rhs effector from Acinetobacter baumannii, revealing a novel mechanism for toxin delivery and activation involving auto-cleavage and domain interaction.
bioRxiv · Nov 18, 2023 · PreprintMicrobiology