A. Wright

Chromosomal fusion drives sex chromosome evolution in treehoppers despite long-term X chromosome conservation

The paper examines X chromosome evolution in treehoppers, finding long-term conservation with one exception of an X-autosome fusion in a species.

Delivery determinants of an Acinetobacter baumannii type VI secretion system bifunctional peptidoglycan hydrolase.

This study identifies the molecular function and delivery determinants of the T6SS effector Tae17 in Acinetobacter baumannii, showing it is a bifunctional peptidoglycan hydrolase with lytic transglycosylase and amidase activities.

Structure of a Rhs effector clade domain identifies new mechanistic insights into type VI secretion system toxin delivery.

The paper presents the structure of Tse15, a T6SS Rhs effector from Acinetobacter baumannii, revealing a novel mechanism for toxin delivery and activation involving auto-cleavage and domain interaction.

Simulating atmospheric drought: Silica gel packets dehumidify mesocosm microclimates

This study shows silica gel packets effectively simulate atmospheric drought in mesocosms when combined with soil drought treatments, improving understanding of drought impacts on plant communities.

β-arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor

This study shows the vasopressin type 2 receptor can activate G proteins at endosomes both with and without beta-arrestin, challenging existing models of GPCR signaling.

The global anaerobic metabolism regulator fnr is necessary for the degradation of food dyes and drugs by Escherichia coli

This paper shows that the FNR regulator in E. coli is essential for azo bond degradation in the gut, influenced by oxygen and cysteine levels.

SexFindR: A computational workflow to identify young and old sex chromosomes

SexFindR identifies sex chromosomes across species, showing sea lamprey lack somatic sex-linked sequences.

Pneumococcal Colonisation is an Asymptomatic Event in Healthy Adults using an Experimental Human Colonisation Model.

This study investigates whether pneumococcal colonisation in healthy adults is symptomatic using an experimental challenge model, finding it asymptomatic regardless of bacterial density or viral co-colonisation.

Acetazolamide reduces exercise capacity following a five-day ascent to 4559 m on Monte Rosa

This study shows that acetazolamide reduces exercise capacity at high altitude, with greater effects in older individuals.