Cancer cell genetics shaping of the tumor microenvironment reveals myeloid cell-centric exploitable vulnerabilities in hepatocellular carcinoma
C. F. Ramirez, D. Taranto, M. Ando-Kuri, M. H. de Groot, E. Tsouri, Z. Huang, D. de Groot, R. J. Kluin, D. J. Kloosterman, J. Verheij, J. Xu, S. Vegna, L. Akkari
This study identifies how cancer genetics shape the tumor microenvironment in hepatocellular carcinoma, revealing myeloid cell-specific vulnerabilities that can be targeted with GM-CSF inhibition.
bioRxiv · Oct 29, 2023Cancer Biology