Macrophage Scavenger Receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease
O. Govaere, S. K. Petersen, N. Martinez-Lopez, J. Wouters, M. Van Haele, R. M. Mancina, O. Jamialahmadi, O. Bilkei-Gorzo, P. B. Lassen, R. Darlay, J. Peltier, J. M. Palmer, R. Younes, D. Tiniakos, G. P. Aithal, , A. Hartlova
This study identifies MSR1 as a key mediator of lipid-induced inflammation in NAFLD, showing its role in macrophage activation and potential as a therapeutic target.
bioRxiv · Feb 1, 2020Immunology