Author

O. Govaere

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

M. Vacca· 2 shared A. Goralcyzk· 1 shared A. Hartlova· 1 shared A. K. Daly· 1 shared B. Barksby· 1 shared B. Topal· 1 shared C. Griffiths· 1 shared C. Mein· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

M. Vacca

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TLR5 drives metabolic dysfunction-associated steatohepatitis through lipid- and flagellin-induced hepatocyte injury signalling

W. Li, N. Wang, R. Kumar, I. Gines Mir, U. Gill, G. Hood, J. Brindley, C. Mein, J. Boot, R. Wilcox, N. Dufton, R. Goldin, J. Loy, K. Devalia, H. Malik, , W. Alazawi

The paper investigates TLR5's role in MASH and fibrosis using clinical data, single-cell transcriptomics, and in vitro models, finding TLR5 drives hepatocyte injury and fibrosis through flagellin and lipid pathways.

bioRxiv · Feb 7, 2026 · PreprintMolecular Biology

Macrophage Scavenger Receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease

O. Govaere, S. K. Petersen, N. Martinez-Lopez, J. Wouters, M. Van Haele, R. M. Mancina, O. Jamialahmadi, O. Bilkei-Gorzo, P. B. Lassen, R. Darlay, J. Peltier, J. M. Palmer, R. Younes, D. Tiniakos, G. P. Aithal, , A. Hartlova

This study identifies MSR1 as a key mediator of lipid-induced inflammation in NAFLD, showing its role in macrophage activation and potential as a therapeutic target.

bioRxiv · Feb 1, 2020Immunology

A novel bioreactor technology for modelling fibrosis in human and rodent precision-cut liver slices.

H. Paish, L. Reed, H. Brown, M. Bryan, O. Govaere, J. Leslie, B. Barksby, J. French, S. White, D. Manas, S. Robinson, G. Spoletini, C. Griffiths, D. Mann, L. Borthwick, , F. Oakley

This paper develops a bioreactor system that extends the viability of precision-cut liver slices (PCLS) to 6 days under normoxic conditions and demonstrates its use in modeling fibrogenesis and testing anti-fibrotic drugs.

bioRxiv · May 25, 2018Cell Biology