Design, synthesis and cellular characterization of a new class of IPMK kinase inhibitors
Y. Zhou, P. Chapagain, D. Desmarini, D. Uredi, L. E. Rameh Plant, J. T. Djordjevic, R. D. Blind, X. Wang
This study designs, synthesizes, and characterizes a new class of IPMK kinase inhibitors, showing reduced glioblastoma cell growth and a novel InsP5 metabolic signature.
bioRxiv · May 9, 2024Pharmacology & Toxicology