Author

P. Chapagain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

R. D. Blind· 2 shared A. R. Ali· 1 shared A. T. Hale· 1 shared D. Desmarini· 1 shared D. T. Kidane· 1 shared D. Uredi· 1 shared E. A. Stivision· 1 shared G. A. Sowd· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersPharmacology & Toxicology

R. D. Blind

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Design, synthesis and cellular characterization of a new class of IPMK kinase inhibitors

Y. Zhou, P. Chapagain, D. Desmarini, D. Uredi, L. E. Rameh Plant, J. T. Djordjevic, R. D. Blind, X. Wang

This study designs, synthesizes, and characterizes a new class of IPMK kinase inhibitors, showing reduced glioblastoma cell growth and a novel InsP5 metabolic signature.

bioRxiv · May 9, 2024Pharmacology & Toxicology

Bilirubin is a new ligand for nuclear receptor Liver Receptor Homolog-1.

P. Chapagain, Z. Haratipour, M. M. Malabanan, W. J. Choi, R. Blind

This study identifies bilirubin as a direct ligand for LRH-1, showing it modulates LRH-1 activity and gene regulation in liver cells.

bioRxiv · May 5, 2024 · PreprintBiochemistry

IPMK regulates HDAC3 activity and histone H4 acetylation in human cells.

G. A. Sowd, E. A. Stivision, P. Chapagain, A. T. Hale, J. C. Poland, L. E. Rameh, R. D. Blind

This study shows IPMK regulates HDAC3 activity and histone H4 acetylation in human cells through inositol phosphate production.

bioRxiv · Apr 29, 2024 · PreprintBiochemistry

sRNAs enriched in outer membrane vesicles of pathogenic Flavobacterium psychrophilum interact with immune genes of rainbow trout

P. Chapagain, A. R. Ali, D. T. Kidane, M. Farone, M. Salem

This study identifies sRNAs in OMVs of Flavobacterium psychrophilum that interact with immune genes in rainbow trout, suggesting a role in modulating host immune responses.

bioRxiv · Dec 22, 2021 · PreprintMicrobiology