Monoclonal antibody chP3R99 reduces subendothelial retention of atherogenic lipoproteins in Insulin-Resistant rats: Acute treatment versus long-term protection as an idiotypic vaccine for atherosclerosis
Y. Soto, A. Hernandez, R. Sarduy, V. Brito, S. Marleau, D. Vine, A. M. Vazquez, S. D. Proctor
This study shows that chP3R99 reduces lipoprotein retention in insulin-resistant rats through acute treatment or long-term vaccination, with no adverse metabolic effects.
bioRxiv · Aug 30, 2023 · PreprintPathology