Author

D.-E. Pefani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Assay:proteomics· 1

Frequent Co-Authors

E. O'Neill· 2 shared M. Chatzifrangkeskou· 2 shared A. Panagopoulos· 1 shared D. Karamitros· 1 shared D. Pankova· 1 shared F. Willenbrock· 1 shared G. Velimezi· 1 shared I. Vendrell· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

E. O'Neill

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2 papers

Recent·Most cited

53BP1 mediated recruitment of RASSF1A at ribosomal DNA breaks facilitates local ATM signal amplification

S. Tsaridou, G. Velimezi, F. Willenbrock, M. Chatzifrangkeskou, A. Panagopoulos, D. Karamitros, V. G. Gorgoulis, Z. Lygerou, E. O'Neill, D.-E. Pefani

The paper identifies RASSF1A's role in recruiting at rDNA breaks to amplify ATM signals and maintain genome stability, showing its loss leads to DNA damage and reduced cell viability.

bioRxiv · Nov 17, 2021 · PreprintCell Biology

RASSF1A Is Required For The Maintenance Of Nuclear Actin Levels

M. Chatzifrangkeskou, D.-E. Pefani, M. Eyres, I. Vendrell, R. Fischer, D. Pankova, E. O'Neill

This study identifies RASSF1A as a regulator of nuclear actin levels by supporting exportin-6 binding to RAN GTPase, linking it to tumor suppression through MRTF/SRF regulation.

bioRxiv · Feb 24, 2019Cell Biology