Author

M. Eyres

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

E. O'Neill· 3 shared D. Pankova· 2 shared A. Blake· 1 shared A. Burns· 1 shared A. G. Abraham· 1 shared A. Hubert· 1 shared A. M. Grawenda· 1 shared A. Sabbagh· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCancer Biology

E. O'Neill

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Author profile →

3 papers

Recent·Most cited

RASSF1C oncogene elicits amoeboid invasion, cancer stemness and invasive EVs via a novel SRC/Rho axis

M. L. Tognoli, N. Vlahov, S. Steenbeek, A. M. Grawenda, M. Eyres, D. Cano-Rodriguez, S. Scrace, C. Kartsonaki, A. von Kriegsheim, E. Willms, M. Wood, M. G. Rots, J. van Rheenen, E. O'Neill, D. Pankova

This study shows RASSF1C promotes amoeboid invasion, cancer stemness, and invasive extracellular vesicles through SRC/Rho axis activation in breast cancer.

bioRxiv · Jan 5, 2021Cancer Biology

TET2 drives 5hmc marking of GATA6 and epigenetically defines pancreatic ductal adenocarcinoma transcriptional subtypes

M. Eyres, S. Lanfredini, A. Burns, A. Blake, F. Willenbrock, R. Goldin, D. Hughes, S. Hughes, A. Thapa, D. Valoulis, A. Hubert, Z. D'Costa, A. Sabbagh, A. G. Abraham, C. Blancher, , E. O'Neill

This study identifies TET2-driven 5hmc loss at GATA6 as a mechanism defining PDAC transcriptional subtypes and shows that TET2 stabilization with Metformin and Vitamin C reverses squamous-like tumor features.

bioRxiv · Oct 22, 2020Cancer Biology

RASSF1A Is Required For The Maintenance Of Nuclear Actin Levels

M. Chatzifrangkeskou, D.-E. Pefani, M. Eyres, I. Vendrell, R. Fischer, D. Pankova, E. O'Neill

This study identifies RASSF1A as a regulator of nuclear actin levels by supporting exportin-6 binding to RAN GTPase, linking it to tumor suppression through MRTF/SRF regulation.

bioRxiv · Feb 24, 2019Cell Biology