Molecular BiologybioRxivPreprint
Gene Activation and repression by the glucocorticoid receptor are mediated by sequestering Ep300 and two modes of chromatin binding
Avital Sarusi-Portuguez, Ivana Grbeša, Moran Tal…·Ofir Hakim
This study identifies how the glucocorticoid receptor (GR) activates or represses genes by sequestering Ep300 and interacting with other transcription factors in 3D chromatin structures.