Scalable Production of a De Novo SARS-CoV-2 Antiviral miniprotein in Escherichia coli
Jinhwan Shin, Eu-min Kim, Jun-Hong Jang, Seok-won Jee, Sang-Hoon Kim, Seong Gwan Yu, Minguen Yoon, Daniel Craig, Ryan Swoyer, Sandip Patel, Praveen Alamuri, Albert E. Price, Rashmi Ravichandran, Lauren P. Carter, Sam Pallerla
This paper describes the scalable production of a de novo SARS-CoV-2 antiviral miniprotein in E. coli, achieving high purity and yield for preclinical and clinical use.
Pharmaceutics · Sep 3, 2026Peer-reviewedBioengineering