CXCL13-CXCR5 Signaling in CD8⁺ T Cell Recruitment and Lymphoid Immune Organization in Clear Cell Renal Cell Carcinoma
Daniel D Shapiro, Kye D Nichols, M Violet Lee, Pavlos Msaouel, Yuanshan Li, Yang Zong, Rong Hu, Wei Huang, Karla Esbona, Toshi Kinoshita, Paz Lotan, Daniel F. Roadman, Everlyne N. Nkadori, Stephanie M. McGregor, David J. Beebe, , Edwin Jason Abel
This study identifies CXCL13-CXCR5 signaling as critical for CD8 T cell recruitment and immune organization in ccRCC, with potential as a biomarker and therapeutic target.
Cancer Immunology Immunotherapy · Jul 7, 2026Peer-reviewedCancer Biology