Author

Daniel Rosas-Rivera

Gladstone Institutes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Jennifer A. DoudnaiD· 2 shared Jingkun ZengiD· 2 shared Longhui QiuiD· 2 shared Min Hyung KangiD· 2 shared Wayne NgoiD· 2 shared Alan AshworthiD· 1 shared Arushi Singhal· 1 shared Chenglong XiaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

Jennifer A. DoudnaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Amplified genome editing by in vivo editor production

Wayne Ngo, Daniel Rosas-Rivera, Kevin M. Wasko, Longhui Qiu, Min Hyung Kang, Shaan Gogna, Jingkun Zeng, Mason T. Hooks, Jamie L. Y. Wu, Z. Li, Jennifer A. Doudna

This study demonstrates that in vivo delivery of genome editing enzymes can be amplified through cell-to-cell transfer, significantly increasing editing efficiency in mice.

bioRxiv · Sep 7, 2026 · PreprintBioengineering

Selective Elimination of TP53 Mutant Cells by Transcript-Activated Chromatin Shredding

Jingkun Zeng, Zhiyuan Cheng, Huadong Chen, Zhaojun Wang, Jared Thompson, Kadin T. Crosby, Hesong Han, Arushi Singhal, Wayne Ngo, Chenglong Xia, Daniel Rosas-Rivera, Zeyuan Terry Zhang, Min Hyung Kang, Ying Mao, Morgan E. Diolaiti, , Jennifer A. Doudna

This paper develops a method to selectively kill cancer cells with TP53 mutations by using RNA-guided Cas12a2 to induce chromatin shredding through targeting cancer-specific transcripts.

Nature · Jun 8, 2026Peer-reviewedCell Biology